Discovery Park Undergraduate Research Internship Program

"Crystallization of Pharmaceutical Materials"

About the Project

Project Time & Type:
Summer 2015 - DURI
Research area(s):
drug development; solid-state chemistry; molecular modeling
Project Description:
The goal of this project is to produce a new crystalline form of a drug-like molecule and develop possible hypotheses about the formation mechanism. The student will conduct crystallization experiments, instrumental analyses including powder X-ray diffraction and scanning calorimetry, and molecular modeling and computation. It is expected that the student will gain fundamental understanding of how the chemistry of a molecule plays out through the phase transition process.
Expected Student Contributions:
We have conducted preliminary studies of the project. The undergraduate student will carry the project forward by systematically examining experimental conditions and control variables. He or she will then teach us the finding and further explore underlying mechanisms from discussion with the PI and graduate students. The interaction can greatly develop the critical thinking and problem-solving skills of the student.
Related Website(s):
Desired Qualifications:
Minimal two years of chemistry training.
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 4 credit hours

Professor in Charge

Li, Tonglei
industrial and physical pharmacy

Student Supervisor

Rubayat Khan
Graduate Student

Cooperating Faculty

Candace Tsai
Health Sciences