Discovery Park Undergraduate Research Internship Program

"Non-Invasive cholesterol measurement"

About the Project

Project Time & Type:
Fall 2015 - DURI
Research area(s):
Biomedical Engineering
Project Description:
Approximately 30 million Americans are at risk for vascular disease, which includes stroke, peripheral arterial disease (PAD), carotid artery disease and aortic aneurysms. One of the reasons for this is high cholesterol amount. The amount of cholesterol in our bloodstream is important because of its role in various cardiovascular diseases. Everyone's body needs cholesterol, but only a limited amount. A soft fat-like substance, cholesterol aids vital bodily functions such as building new cells and producing hormones. Cholesterol is carried through the bloodstream by attaching to certain proteins. The combination is called a lipoprotein. The risk of developing these conditions is complex and depends not only on how much cholesterol but also what kind of cholesterol you have in your blood. Generally speaking, high levels of LDL -- the "bad cholesterol" -- are associated with increased risk of developing coronary heart disease; high levels of HDL -- or "good cholesterol" -- are associated with decreased risk. LDL cholesterol collects in the walls of arteries, initiating "hardening of the arteries" or atherosclerosis. People with atherosclerosis are in turn vulnerable to heart failure, heart attack, stroke, and other problems caused by clogged blood vessels. Even so, some people who have high LDL cholesterol never actually get heart disease, and many heart attack victims do not have abnormally high cholesterol levels. It is critical to have non- or less invasive cholesterol monitor to check if often, so that the problem of LDL cholesterol is measured easily. Towards this, this project aims to design and develop a monitor for this.
Expected Student Contributions:
Do the literarure survey, come up with design, build, and test it.
Related Website(s):
Desired Qualifications:
Junior or senior 3.5 and above GPA Interest and willing to learn and working independently
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Sundararajan, Rajeswari
school of engineering technology

Student Supervisor

Raji Sundararajan

Cooperating Faculty

Ignacio Camarillo
Biological Sciences