Discovery Park Undergraduate Research Internship Program

"TOPRS: Vitamin D and Fat Cells"

About the Project

Project Time & Type:
Full-Year 2016 - DURI
Research area(s):
TOPRs, obesity, vitamin D
Project Description:
Our current project aims to investigate how vitamin D regulates of adipocyte lipid metabolism, an area which remains largely unstudied. To do this, we utilize a cell line that we are able to differentiate into mature adipocytes, and examine the effects of the bioactive vitamin D metabolite, 1,25-dihydroxyvitamin D (1,25(OH)2D), on the adipocyte’s ability to store and metabolize lipid. These data will contribute to our understanding of vitamin D regulation of adipose tissue physiology, and under what conditions vitamin D might be able to modulate adipose tissue in order to reduce the severity of obesity and associated metabolic disturbances.
Expected Student Contributions:
The intern will have an independent research project with day to day guidance of a graduate student in the laboratory. The intern will learn to culture, treat and harvest mammalian cells in culture. In addition, the intern will learn and complete assays, such as protein assays, Western blotting and rtPCR.
Related Website(s):
Desired Qualifications:
Previous experience in a laboratory is preferred, but not required. A background in areas related to biology is required.
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Teegarden, Dorothy
nutrition science

Student Supervisor

Dorothy Teegarden

Cooperating Faculty

Shawn Donkin
Animal Science, Agriculture