Discovery Park Undergraduate Research Internship Program

"TOPRS: Molecular Mechanisms of Dietary Fat Absorption"

About the Project

Project Time & Type:
Full-Year 2016 - DURI
Research area(s):
Obesity, Lipid Metabolism, Proteomics
Project Description:
Dietary fat is the most energy dense nutrient consumed. Therefore, it plays an important role in energy balance and contributes to health problems like obesity when consumed in excess. Our laboratory is interested in understanding the molecular mechanisms of dietary fat absorption to allow us to prevent or treat these problems by better dietary recommendations and or developing drugs to intervene in this pathway. Currently, we are interested in better understanding the role of lipid droplets within the absorptive cells of the intestine, enterocytes, in the process. To do this, we are currently identifying proteins that localize to lipid droplets to better understand their biology.
Expected Student Contributions:
I imagine the intern helping with analysis of proteomics data from the current projects that are ongoing in the lab. We are following up on specific proteins or types of proteins identified using biochemical and molecular techniques. Depending on the proteins identified, a student may take a different path; however, types of laboratory analyses like Western Blotting, Confocal Microscopy, and Lipid Analysis will be performed.
Related Website(s):
Desired Qualifications:
>3.5 GPA Course work in chemistry and biology - required Course work in nutrition - preferred, but not required Previous lab experience - preferred, but not required
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Buhman, Kimberly
Nutrition Science/HHS

Student Supervisor

Kim Buhman
Associate Professor

Cooperating Faculty