Discovery Park Undergraduate Research Internship Program

"Development of Novel Biomaterials-based Strategies for Tissue Repair and Regeneration"

About the Project

Project Time & Type:
Spring 2015 - DURI
Research area(s):
Biomaterials, Nanotechnology, Cell/Tissue Engineering
Project Description:
Tissue engineering provides an interdisciplinary platform to generate functional tissues involving the use of biomaterials, cells, and biological factors alone or in combination. In this work, we are particularly interested in developing novel polymeric scaffolds to deliver myoblasts and biological factors to promote muscle regeneration. Moreover, we aim to adopt ex vivo gene transfer strategy to modify myoblasts before transplantation. The modification are expected to promote myogenesis and angiogenesis, which are both critical for successful muscle regeneration. The knowledge from this project will shed light on how to increase the survival rates and the long-term engraftment capacity of transplanted myoblastst, both of which are limiting factors in the current myoblast transplantation strategy.
Expected Student Contributions:
Our research group welcomes highly motivated undergraduate students to learn and make contributions in regenerative engineering. The intern will closely work with a postdoctoral fellow in our lab and assist in the synthesis, characterization, and optimization of polymeric scaffolds to achieve appropriate combination of physico-chemical and biological properties. The student will also gain experience in cell culture techniques and translational research.
Related Website(s):
Desired Qualifications:
GPA > 3.5. Highly motivated, responsible, and dedicated learner and researcher.
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Deng, Meng
agricultural and biological engineering

Student Supervisor

Chunhui Jiang

Cooperating Faculty

Shihuan Kuang
Animal Sciences