Discovery Park Undergraduate Research Internship Program

"Electro-cancer therapy"

About the Project

Project Time & Type:
Spring 2015 - DURI
Research area(s):
Biomedical engineering
Project Description:
With six American women diagnosed with breast cancer and one dying every 13 minutes, the need for alternate, safe, affordable and effective treatment cannot be overstated. Affordability is a critical issue as 62% of all foreclosures and bankruptcies in the US are due to medical expenses. Towards this, electrical pulse-mediated chemo drug delivery, known as Electrochemotherapy, is a boon to these patients, especially to those who have inoperable or chemo-resistant or radio-resistant. In this project, various cell lines, including MCF-7, breast cancer cells will be treated with various cancer drugs and curcumin, the yellow pigment of turmeric, the Indian gold spice using electrical pulses of various voltages and durations. Their efficacy will be characterized using trypan blue viability assay and other assays at various doses.
Expected Student Contributions:
Do the experiments and the assays, anlyze the results and prepeare reports/conference papers/ppts
Related Website(s):
Desired Qualifications:
3.5 and above junior/senior interest and willing to learn and schedule that allows enough time for this
Estimated Weekly Hours:
Department awards independent research credits for this project?

Professor in Charge

Sundararajan, Rajeswari
school of engineering technology

Student Supervisor

Rajeswari Sundararajan

Cooperating Faculty

Ignacio Camarillo
Biological Sciences