Discovery Park Undergraduate Research Internship Program

"Electro-cancer-drug delivery"

About the Project

Project Time & Type:
Fall 2013 - DURI
Research area(s):
Project Description:
With a American woman dying every 13 minutes, the need for alternate, safe, and effective treatment cannot be overstated. In addition it has to be economical, as many foreclosures and bankruptcies are due to medical expenses. Towards this end, electrical pulse-mediated chemo drug delivery is a boon, especially to those patients who have inoperable tumors and whose tumors are chemo-resistant and radio-resistant. In this project, various cell lines, such as MCF-7, breast cancer cells will be treated with various cancer drugs and curcumin, the yellow pigment of turmeric, the Indian gold spice using electrical pulses of various voltages and durations. Their efficacy will be characterized using trypan blue viability assay and other assays at various doses.
Expected Student Contributions:
do cull culture of cancer cells prepare samples for electroporation conduct electroporation do viability and other assays analyze resuslt and prepare weekly reports and a conference paper/poster
Related Website(s):
Desired Qualifications:
3.5 GPA or above Previous cull culture experience is a plus/preferred willing to learn and work independently need 3 continuous hours to perform research-each slot
Estimated Weekly Hours:
Department awards independent research credits for this project?

Professor in Charge

Sundararajan, Rajeswari
Electrical and Computer Engineering Technology

Student Supervisor

Raji Sundararajan

Cooperating Faculty

Ignacio Camarillo
Biological Sciences