Discovery Park Undergraduate Research Internship Program

"Graphene-based Glucose Sensors with Integrated Power"

About the Project

Project Time & Type:
Summer 2013 - DURI
Research area(s):
Biosensing, nanomaterials
Project Description:
The most commonly used monitoring and assessment system used in diabetes detection and management is the enzyme-based finger-pricking method. This procedure is however is inconvenient, invasive, prone to contamination, expensive, requires patient compliance, and needs constant attention to ensure timely dosing in order to prevent complications. Given these limitations, a less invasive, relatively inexpensive and continuous monitoring system would be a good step forward in diabetes healthcare. Nanotechnology-inspired biosensors could provide a way forward. Nanomaterials such as carbon nanotubes (CNTs) and metallic nanoparticles exhibit impressive results in electrochemical biosensing. In particular, they exhibit high sensitivity, low detection limits and, if properly packaged and implanted, for example, could provide the continuous monitoring needed for effective diabetes healthcare. Several promising nanomaterial-inspired glucose sensors have been fabricated and point towards commercially viable glucose sensors that could replace the finger-pricking method. These sensors, however, invariably require complex fabrication methods involving lithography and multi-step chemical processing that are expensive and unsuitable for a wide variety of materials, thus prohibiting low-cost commercial sensor designs. A promising new nanomaterial-based biosensor has been designed by Claussen et al [7]. The sensor is based on multilayered graphene petal nanosheets (MGPNs), with glucose oxidase (GOD) as a biorecognition element for glucose detection. This platform will be developed during this summer project, with particular focus on integration of the biosensor with an electrical energy storage element made of the same material.
Expected Student Contributions:
The work will be highly experimental. The intern student will focus on material integration of both the biosensor (e.g., electrodeposition of functional materials onto the petals) and capacitive materials for the electrical storage component.
Related Website(s):
Desired Qualifications:
high GPA > 3.5, willingness to learn experimental laboratory procedures.
Estimated Weekly Hours:
Department awards independent research credits for this project?

Professor in Charge

Fisher, Timothy
mechanical engineering

Student Supervisor

Kwesi Adarkwa
Graduate Student

Cooperating Faculty

Babak Ziaie
Electrical Engineering
Jenna Rickus
Ag and Bio Engineering