Discovery Park Undergraduate Research Internship Program

"Assessment of particles upon processing"

About the Project

Project Time & Type:
Fall 2012 - DURI
Research area(s):
Material Sciences, Mechanical Engineering, ABE and ChE
Project Description:
Milling is a unit operation during the manufacture of active ingredients for the reduction of particle size and for the increase of surface area, both necessary for the development of pharmaceutical products. Physico-chemical characteristics such as interactions, moisture sorption, bulk mechanical properties, triboelectric charging behavior, dissolution rate and physical or chemical stability of a material are changed by the reduction of particle size and potential presence of phase transformations. The project deals with systematic characterization of some of the properties for material insight and further deal with controlling behavior.
Expected Student Contributions:
The candidate student will be trained with the appropriate instrumentation for characterization. It will be explained to the candidate the aims of the research. Since methodology needs to be developed, the student needs to get involved by offering input on the design and implementation of the steps to follow for the methods.
Related Website(s):
Desired Qualifications:
GPA is helpful but not necessary as long as the student is motivated, committed and reliable. It would be very helpful if the student has had some courses on crystal structures, physicochemical or thermodynamics. Sophomores and higher will be considered.
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Pinal, Rodolfo
industrial and physical pharmacy

Student Supervisor

Andrew Otte
Post-doctoral associate

Cooperating Faculty

Teresa Carvajal
John Blendell