Discovery Park Undergraduate Research Internship Program

"Toxicity study of Electroporation of cancer cells with and without drug/gene delivery "

About the Project

Project Time & Type:
Fall 2011 - DURI
Research area(s):
Biomedical engineering
Project Description:
Electroporation is the technqiue of applying high intensity, short duration (micro and milliseconds) pulses to enhance the permeability of drug molecules that are impermeable otherwise. This has high efficay due to its targeted delivery intratumorally. It is practical interest to study the efficicy of this technique with respect to its toxicity compared to the untreated control, drug only, and electrical pusles only, as well as charcaterize it for its permeability, etc. using laser scan microscopy, and other technqiues.
Expected Student Contributions:
Do cell culture work Do electroporation of cells Do the toxicity and other characterization studies
Related Website(s):
None
Desired Qualifications:
Senior or Junior, with good cell culture experience 3+ GPA Interest and willing to learn new things and explore
Estimated Weekly Hours:
10
Department awards independent research credits for this project?
No

Professor in Charge

Name:
Sundararajan, Rajeswari
Deptartment/College:
electrical and computer engineering tech

Student Supervisor

Name:
Raji Sundararajan
Title:
Associate Professor

Cooperating Faculty

Name:
Ignacio Camarillo
Deptartment/College:
Biological Sciences
Name:
Jim Leary
Deptartment/College:
Biomedical Engineering, Basic Medical Sciences