Discovery Park Undergraduate Research Internship Program

"Novel hydrocolloids as low cost wound dressings"

About the Project

Project Time & Type:
Fall 2010 - DURI
Research area(s):
Biomedical Engineering, Chemistry, Biology
Project Description:
We have recently developed a unique low-cost wound dressing in the laboratory. This hydrocolloid (gel-like) is intended for use on superficial injuries, ulcers and post-surgical wounds. The gel maintains a moist wound environment for healing, absorbs body fluids and is also anti-bacterial. We hypothesize that the gel's anti-bacterial properties come from its ability to draw water out of bacteria (osmosis). Therefore, the projects aim is to perform a series of experiments that characterize the bactericidal properties of various gel formulations and confirm the mechanism of action for a wide range of microbes. This research has far reaching implications in the field of low-cost healthcare delivery.
Expected Student Contributions:
The intern will be responsible for the fabrication and physical characterization of the hydrocolloid mixes. In addition, the intern will be performing bioactivity assays to measure the bactericidal properties. Many of these assays will be standard agar dish cultures with non-virulent bacterial strains.
Related Website(s):
Desired Qualifications:
Students with a 3.0+ GPA and at least a sophomore standing. Majors in Biology, Chemistry and Biomedical Engineering are preferred. Previous experience with bacterial/cell cultures is also valuable.
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Li, Jianming
center for paralysis research (BMS)

Student Supervisor

Jianming Li
Post Doctoral Fellow

Cooperating Faculty

Richard Borgens