Discovery Park Undergraduate Research Internship Program

"Bio/Pharmaceutical Lyophilization "

About the Project

Project Time & Type:
Fall 2016 - DURI
Research area(s):
Biotechnology, Manufacturing, Nanotechnology
Project Description:
Freeze-drying, also called lyophilization, is widely used in manufacturing of injectable pharmaceuticals, vaccines, biotech products, chemical reagents, food and probiotic cultures and as a processing step in nanostructure synthesis. The research during this DURI project will involve investigation of various process analytical technologies for measuring heat and mass transfer in R&D lyophilizers. Comparison of different sensor technologies for lyophilized formulations and results of heat and transfer modeling will be done with experimental data collected in the LyoHUB laboratory facility at Birck nanotechnology center.
Expected Student Contributions:
The undergraduate researcher will be involved in developing experimental procedures, analysis of results and communication of findings to academic and industrial collaborators.
Related Website(s):
Desired Qualifications:
Chemical Engineering and related majors; heat and mass transfer fundamentals; laboratory procedures; programming; CAD and simulations.
Estimated Weekly Hours:
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Alexeenko, Alina
aeronautics and astronautics

Student Supervisor

Andrew Strongrich
Graduate Student

Cooperating Faculty

Elizabeth Topp
Industrial and Physical Pharmacy
Dimitrios Peroulis
Electrical and Computer Engineering