Discovery Park Undergraduate Research Internship Program

"2. Development of Responsive Hydrogel Vehicles for Controlled Delivery of Analgesics"

About the Project

Project Time & Type:
Fall 2016 - DURI
Research area(s):
Biomaterials, Cell/Tissue Engineering
Project Description:
Controlled drug delivery offers numerous advantages when compared to conventional dosage forms including improved efficacy, reduced toxicity, reduced need for specialized drug administration, and improved patient compliance/convenience. In this project, we are particularly interested in developing responsive hydrogel as a controlled delivery vehicles because hydrogels composed of polymer networks swollen in water possess many properties including cytocompatibility, controllable physical properties, and minimally invasive surgical delivery via injection. However, the utility of conventional hydrogels for clinical applications is often hampered by their inferior mechanical performance. This study aim to develop and characterize responsive and elastic injectable hydrogels. This hydrogels will be tested for their potential application in intraarticular drug delivery of analgesics.
Expected Student Contributions:
Our research group welcomes highly motivated undergraduate students to learn and make contributions in translational biotechnology. The intern will closely work with postdoctoral fellows in our lab and assist in the synthesis, characterization, and optimization of responsive and elastic injectable hydrogels to achieve appropriate combination of physico-chemical and biological properties. The student will also gain experience on biomaterial evaluation both in vitro and in vivo.
Related Website(s):
www.regenerativematter.com
Desired Qualifications:
GPA > 3.5. Highly motivated, responsible, and dedicated learner and researcher
Estimated Weekly Hours:
9
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Name:
Deng, Meng
Deptartment/College:
agricultural and biological engineering

Student Supervisor

Name:
Liangju Kuang
Title:
Postdoctoral Fellow

Cooperating Faculty

Name:
breur@purdue.edu
Deptartment/College:
Veterinary Clinical Sciences