Discovery Park Undergraduate Research Internship Program

"Vitamin D regulation of breast cancer prevention "

About the Project

Project Time & Type:
Full-Year 2017 - CPIP
Research area(s):
Vitamin D regulation of breast cancer prevention
Project Description:
A variety of studies suggest that better vitamin D status is associated with reduced risk of breast cancer. As tumors develop, energy metabolism is altered including glucose, glutamine and lipid metabolism. Our laboratory has shown that vitamin D metabolites regulate energy metabolism during cancer progression. In this project, breast epithelial cells that are normal and during progression to cancer will be used, which are representative of multistage cancer progression, to study how the effects of vitamin D alter energy metabolism during progression of cells to cancer.
Expected Student Contributions:
The student will participate in mammalian cell culture and quantification of gene transcription and protein expression; potentially learn to use chemical inhibitors, reporter gene assay and other basic techniques for molecular biology.
Related Website(s):
http://www.purdue.edu/hhs/nutr/directory/faculty/teegarden_dorothy.html
Desired Qualifications:
Prefer, but not necessary, previous experience with nutrition or biology laboratory courses, biology and biochemistry courses, and interested in vitamin D and cancer.
Estimated Weekly Hours:
6
Department awards independent research credits for this project?
Yes, 3 credit hours

Professor in Charge

Name:
Teegarden, Dorothy
Deptartment/College:
nutrition science

Student Supervisor

Name:
Dorothy Teegarden
Title:
Professor

Cooperating Faculty

Name:
Shawn Donkin
Deptartment/College:
Animal Science/Agriculture