Discovery Park Undergraduate Research Internship Program

"Electrical field study of biological organs due to electroporation"

About the Project

Project Time & Type:
Fall 2015 - DURI
Research area(s):
Biomedical Engineering
Project Description:
Electroporation is a technique that involves the application of electrical pulses of high intensity and short duration to enhance the uptake of normally impermeable drugs and genes for cancer across the plasma membrane. The electric field intensity and distribution is a critical factor to achieve the delivery of the chemo drugs/genes. In this project, it is proposed to study the electrical modeling/simulation of various organs, such as liver, with respect to their application in cancer therapy, using electroporation, at various pulse and needle configurations.
Expected Student Contributions:
Simulation of electric field distribution using freely available/downloadbale industrial standard commercial software
Related Website(s):
Desired Qualifications:
junior or senior 3.5+ GPA willing and capable of working independently, learning the software and apply it to study the electric field distribution in organs, such as liver, where most of the metasatses occur due to breast and other cancers
Estimated Weekly Hours:
Department awards independent research credits for this project?

Professor in Charge

Sundararajan, Rajeswari
school of engineering technology

Student Supervisor

Raji Sundararajan

Cooperating Faculty

Ignacio Camarillo
Biological Sciences